Cases of myopathy and rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported with statins, including CRESTOR. AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases.
AstraZeneca provides this link as a service to website visitors. These reports are generally nonserious and reversible upon statin discontinuation.
Such products and services include an integrated suite of health services, such as medical, dental, behavioral health, pharmacy, vision, supplemental benefits, and other related products including group life, accident and disability insurance. All patients should be advised to promptly report unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever, and if muscle signs and symptoms persist after discontinuing CRESTOR.
CRESTOR is contraindicated in patients with a known hypersensitivity to any component of this product, in patients with active liver disease, which may include unexplained persistent elevations of hepatic transaminase levels, in women who are pregnant or may become pregnant, and in nursing mothers.
I disagree I agree. This preferred status applies to both those who are determined to be at higher risk and those at lower risk who are not getting enough cholesterol lowering from treatment with a generic statin.
You have selected a link that will take you to a site maintained by a third party who is solely responsible for its contents. AZN to help ensure that customers are given an appropriate cholesterol-lowering medication based on their treatment need. Based on clinical trial data with CRESTOR, in some instances these increases may exceed the threshold for the diagnosis of diabetes mellitus.
In the controlled clinical trials database, the most common adverse reactions were headache 3. Important notice for users You are about to access AstraZeneca historic archive material. Please refer to your approved national product label SmPC for current product information.
By using this website you consent to our use of these cookies. Cigna maintains sales capability in 30 countries and jurisdictions, and has approximately 80 million customer relationships throughout the world. Any reference in these archives to AstraZeneca products or their uses may not reflect current medical knowledge and should not be used as a source of information on the present product label, efficacy data or safety data. It is recommended that liver enzyme tests be performed before the initiation of CRESTOR and if signs or symptoms of liver injury occur.
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These risks can occur at any dose level, but are increased at the highest dose 40 mg. There have been rare reports of immune-mediated necrotizing myopathy associated with statin use. Rare postmarketing reports of cognitive impairment eg, memory loss, forgetfulness, amnesia, memory impairment, confusion have been associated with statin use, including CRESTOR.
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