Some people who suffer from Following prolonged therapy with high doses, abrupt discontinuation of TCAs, including imipramine, could lead to withdrawal symptoms such as nauseavomitingdiarrheaor restlessness. We also used our own handsearched database for older studies, and two clinical trials databases.
Four studies reported some information about adverse events, but reporting was inconsistent and fragmented, and the quality of evidence was very low. We found no first or second tier evidence of efficacy. The more common side effects of imipramine in adolescents and adults with depression can include:. Imipramine is used to treat symptoms of depression in adolescents and adults.
Imipramine tablets should not be taken during pregnancy or if breast-feeding. Withdrawals meant that any results were more likely to be per protocol for completers than for a true ITT analysis.
Only Sindrup adequately described how allocation to treatment groups was concealed; the others did not report this. High concentration topical capsaicin may benefit some patients with postherpetic neuralgia Derry Assessing risk of bias in included studies.
Symptoms of overdose may include: Other medications can affect the removal of imipramine from your body, which may affect how imipramine works. Topical capsaicin low concentration for chronic neuropathic pain in adults. European Archives of Psychiatry and Clinical Neuroscience. Imipramine was discovered in A new definition of neuropathic pain. ABT Atypical antipsychotics e.
Treatment of neuropathic pain: See also the Warning section. Pain not assessed separately but as one of set of neuropathy symptoms Neuropathy symptom scores and VAS figures were given for participants. The kidneys of older adults may not work as well as they used to. Pooled analysis of two randomized, placebo-controlled chronic low back pain trials. Keep all medicines away from children and pets.
It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.
Antidepressants are widely used to treat chronic neuropathic pain pain due to nerve damageusually in doses below those at which they exert antidepressant effects. Check the labels on all your medicines e.