The structural formula is as follows:. Because phentermine is a sympathomimetic agent, it is contraindicated in patients with hyperthyroidism. Fatigue and depression usually follow the central stimulation. Phentermine is contraindicated in patients with agitated states.
Epub Mar The risk or severity of adverse effects can be increased when Phentermine is combined with Hydroxyamphetamine.
There is no established use of phentermine in infants. Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen-phen.
Indications and Usage for Phentermine
One case of hypertensive crisis has been reported in a patient taking the recommended dose of another MAO-B inhibitor, selegiline, in combination with ephedrine. To prevent withdrawal reactions, your doctor may reduce your dose gradually.
Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
However, recent data suggest that phentermine's effect on MAO inhibition and serotonin augmentation is minimal at therapeutic doses, and that phentermine does not additionally increase plasma serotonin levels when combined with other serotonergic agents.
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Does phentermine inhibit monoamine oxidase? A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. Patients should be monitored to confirm that the desired antihypertensive effect is achieved.
A Amine oxidase [flavin-containing] A. Skip to Content googletag. Tell your doctor right away if any of these unlikely but serious side effects occur: Methazolamide may decrease the excretion rate of Phentermine which could result in a higher serum level.
The risk or severity of adverse effects can be increased when Phentermine is combined with Acebutolol. A minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese, due to obligatory weight gain that occurs in maternal tissues during pregnancy.
Do not increase your dose, take it more often, or use it for a longer time than prescribed. The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. Other adverse effects include: Anticonvulsant extended release formulation is used. For some patients, half tablet Some products have ingredients that could raise your heart rate or blood pressure. Cardiovascular effects include tachycardia, arrhythmia, hypertension or hypotension, and circulatory collapse.
Properly stop the medication when so directed.